New article on ChemRxiv

Our new publication is now available online.

Abstract: We report the on-resin synthesis of monodisperse (i.e. discrete) polysarcosine compounds and their uses as an hydrophobicity masking entity for the construction of highly-loaded homogeneous antibody-drug conjugates (ADC). The polysarcosine-based drug-linker platform described herein improves drug-loading, physicochemical properties, pharmacokinetics and shows excellent potency in vivo.

Read more about this publication on ChemRxiv.

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