A wholly owned subsidiary of Eli Lilly and Company
Executive Management Team
Managing Director
Frédérique Brune, PharmD
Frédérique Brune has over 20 years’ experience in the field of innovative drug development. Before joining Mablink, Frédérique was VP for Development CMC and Supply Chain at Innate Pharma, a global clinical-stage oncology-focused biotech company developing therapeutic antibodies that harness the immune system to fight cancer. Before that, she spent 10 years in multiple Development Leadership positions at LFB, where she notably oversaw the successful registration of 2 innovative therapeutics. She eventually became LFB’s Quality Director of Bioproduction. Previously, she was Analytical Manager and Project Leader at Pierre-Fabre.
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At Mablink she has the responsibility of the scientific and preclinical development teams. Her primary objective is to oversee all the operations necessary to obtain INDs for Mablink’s pipeline ADCs.
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Frédérique holds a PharmD from Paris-Sud University and an MS in Experimental and Clinical Pharmacology from Pierre & Marie Curie University (now part of Sorbonne University, Paris, France).
Human Resources Director
Gaëlle Vansteene
Gaëlle Vansteene graduated with a master's degree in Human Resources Management from Lille University, supplemented by a degree in Sociology. She has over 20 years of experience as a Human Resources Director in French and international environments, including as Europe HR Director for KLM Dutch Airlines and most recently as HR Director at Sanofi Pasteur MSD for European countries and then France.
As a professional coach and HR consultant for the past 6 years, Gaëlle brings with her HR expertise, a strong interest in people and team development and fulfillment, which are key to the growth and performance of Mablink.
Director of Operation
Valérie Attuil, PhD
Dr Valérie Attuil started her career in academic research, working for 10 years in the fields of virology and immunology. With her solid scientific background, she joined a biotech company, which developed polyclonal and monoclonal antibodies, where she worked for 8 years as a product manager. She liaised between R&D, production and marketing, and was also responsible for developing new products.
In her current position, Valerie is ensuring the seamless execution of the development roadmap, covering the facility and supply management, as well as the IT strategy.
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Valérie Attuil holds a PhD in Immunology from the Ecole Normale Supérieure de Lyon (France).
Management Team
Lenka Kyrych Sadilkova, PhD
Dr. Kyrych Sadilkova started her career with academic institutions, working on bioconjugation and recombinant proteins projects and then on PK/PD modeling.
Lenka brings her skills in non-clinical pharmacology and team management that she has gained during her 9 years at SOTIO Biotech a.s., a Czech biotech company focusing on the development of innovative oncology immunotherapies. After several years as a Pharmacology Lead, she was promoted to the position of Director of Pharmacology responsible for non-clinical development of several ADCs, including one already in Phase I.
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An expert in ADCs with a specific experience in target validation and antibody development, she leads Mablink’s biology laboratory, in close collaboration with the CSO and the CDO, to support the development of Mablink’s ADC candidates.
Lenka holds a PhD in Biochemistry and Molecular Biology and a PhD in Gerontology, both from Charles University (Prague, Czech Republic).
Delphine Bregeon, PhD, PMP®
Delphine Bregeon brings over 15 years’ experience in biotechnology. She previously worked at Innate Pharma, a global clinical-stage oncology-focused biotech company developing therapeutic antibodies that harness the immune system to fight cancer. At Innate, she worked for several years as Scientist and R&D Project Manager developing ADC site-specific conjugation technology before moving to Pharmaceutical Operations where she was in charge of CMC and supply project management on early-stage, late-stage and commercial programs.
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At Mablink she has the responsibility of the management and coordination of all external CMC activities supporting the development of the PSARlink™ linker platform, and of the multiple drug candidates stemming from it.
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Delphine holds a PhD in Organic, Mineral and Industrial Chemistry from the University of Caen (France) and a PMP® certification (Project Management Professional).